I have just read on two blog post by Cormac Hogan and Vaughn Stewart where there seems to be an issue with vSphere 5.x connected to Netapp using NFS. On occasions where there is high load (I/O) the datastores would disconnect or disappear for a period of time and then reappear. There is some work around available which are
1) Reduce the max queue depth down to 64
2) If you have license to use storage I/O control then this would help prevent the issue
3) Upgrade ONTAP to either 7.3.7 P2, 8.0.5 or 8.1.3
We are not currently experiencing these issues but we will be implementing option 1 in case it happens suddenly. In the long run we are planning the upgrade of ONTAP so that we can fix the issues.
Here are the blog posts from Cormac Hogan, Vaughn Stewart and VMware KB article
http://cormachogan.com/2013/02/08/heads-up-netapp-nfs-disconnects/
http://virtualstorageguy.com/2013/02/08/heads-up-avoiding-vmware-vsphere-esxi-5-nfs-disconnect-issues/
http://kb.vmware.com/selfservice/microsites/search.do?language=en_US&cmd=displayKC&externalId=2016122
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